Pentobarbital will decrease the level or effect of aprepitant by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. pentobarbital will decrease the level or effect of vincristine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unknown. pentobarbital will decrease the level or effect of atogepant by affecting hepatic/intestinal enzy... https://wat-is-pentobarbital56790.homewikia.com/11650214/een_beoordeling_van_wat_is_pentobarbital