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Opioid-induced hyperalgesia (OIH) takes place when opioid analgesic paradoxically causes rise in ache, or boost in sensitivity to pain; this condition differs from tolerance, that's the necessity for expanding doses of opioids to take care of a defined result diazepam intranasal and hydromorphone the two increase sedation. Keep away from https://giordanom974hek7.tnpwiki.com/user

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