Most eukaryotic chromosomes bend back again on by themselves to form a Actual physical loop with the telomere. The existence of such loops, aptly named t-loops, was first proven by electron microscopy of purified human telomeres that were stripped of their proteins and stabilized by crosslinking (Griffith et al. Telomeres https://edgaridvmd.tkzblog.com/28181677/detailed-notes-on-endopeel-abdomen-antes-y-después